Comparison of Serum Zinc and Copper Levels in Children with Intractable and Controlled Eplipsy

Epilepsy is one of the most common neurological disorders. as second burdensome neurologic disorder worldwide in terms disability-adjusted life years. Copper (Cu) involved a number enzymes with catalase and oxidase-type reactions. This study aimed to identify role serum copper etiology epilepsy its response treatment Methods: prospective case controlled that was conducted on patients attending Outpatient Neurology Clinic those admitted Pediatric Department at Benha University Hospital Children Hospital. who participate this were classified into two groups; Group I: 60 children epilepsy. II: controls. Serum measured. Results:  showed significantly higher level epileptic cases when compared control groups (P=0.002). intractable subgroups (p=0.035).Conclusion: Higher cupper levels associated suggested be independent risk predictors susceptibility.